Institute For Systems Biology
71% goes to programs $1 to raise $100 Strong reserves
Institute For Systems Biology is a 501(c)(3) organization based in Seattle, Washington, registered in 2000, with $42,255,091 in FY2024 revenue. CharityIndex grades it B+, and it directs about 71% of spending to programs.
401 Terry Ave N, Seattle, WA, 98109 EIN 91-2003593 Since 2000
Revenue (FY2024)
$42.3M
▼ 3.1% vs prior year
Science & Tech median: $288K
Expenses (FY2024)
$47.6M
Net assets
$58.9M
Employees
299
CharityIndex rating
One independent A+ to F grade from four published criteria, each scored separately from IRS filings and combined by weight.
B+
BProgram efficiency40% of the rating71% to programs · $1 to raise $100
Measures how much of every dollar spent actually reaches programs, plus what it costs to raise $100 of donations. The worse of the two measures sets the letter (85%+ to programs is an A; under $15 to raise $100 is an A), averaged over the three most recent filings. For Institute For Systems Biology: 71% to programs · $1 to raise $100 earns a B on this criterion. See the exact thresholds →
C+Financial health25% of the rating15 mo reserves · -13% margin
Measures whether the organization is built to last: how many months its reserves would cover expenses (3+ months earns an A-range score, but hoarding 5+ years of budget is capped) and whether it runs a surplus or a deficit. For Institute For Systems Biology: 15 mo reserves · -13% margin earns a C+ on this criterion. See the exact thresholds →
A+Governance25% of the rating6 of 6 checks met
Checks how the organization is run, from its own Form 990: an independent board majority, a board of five or more, conflict-of-interest, whistleblower and document-retention policies, and independently audited financials. The share of disclosed checks that pass sets the letter. For Institute For Systems Biology: 6 of 6 checks met earns a A+ on this criterion. See the exact thresholds →
A+Transparency10% of the rating5 of 5 disclosure signals
Counts five disclosure signals: a recent filing, a mission statement, program descriptions, a listed website, and the full expense breakdown. More disclosure, better letter. For Institute For Systems Biology: 5 of 5 disclosure signals earns a A+ on this criterion. See the exact thresholds →
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Mission
Using the science of systems biology to predict, prevent and cure disease.
What they do
See schedule oscience education: in 2018, the logan center worked with 8 school districts across the puget sound region on their k-12 science/stem programs; these 8 districts serve over 100,000 students. -students: we provided onsite learning experiences for student groups. these groups consisted of 100 undergraduate students and 100 high school students. -teachers: we provided over 80 days of professional development for secondary science teachers in those districts, which totaled 1064 teacher-days. we also provided 38 professional development days to 10 elementary and middle school teachers participating in a deep learning experience with science and engineering. -principals: we provided a professional learning series for principals in 4 districts. -science curriculum leaders: we provided 21 professional development sessions for science leaders from a collaborative of 35 school districts across king and pierce counties. isb also held various symposia, seminars, and workshops to disseminate basic knowledge about systems biology and create dialog about leading-edge topics. during 2018, 308 external persons attended such events.
Contact & location
- Address
- 401 Terry Ave N, Seattle, WA, 98109
- City
- Seattle
- State
- Washington
- Category
- Science & Technology
- Subcategory
- Biological & Life Sciences
- Phone
- …
- Website
- …
Financial trends
Revenue declined from $45.8M (FY2013) to $42.3M (FY2024) across 12 reported years.
Financial snapshot
Financial health & position (FY2024)
Liabilities $50.4MNet assets $58.9M
Operating margin
-12.5%
Spent more than it raised in the latest fiscal year.
Total assets
$109.3M
Total liabilities
$50.4M
Net assets
$58.9M
Salaries & benefits
$24.1M
51% of expenses
Board members
16
12 independent
Financials by year
| Fiscal year | Revenue | Expenses | Net assets | Total assets | Form |
|---|---|---|---|---|---|
| 2024 | $42,255,091▼3.1% | $47,550,054▲1.7% | $58,859,496▼6.0% | $109,279,173▼9.8% | 990 |
| 2023 | $43,611,326▲17.6% | $46,752,331▲11.4% | $62,630,122▲1.5% | $121,196,657▼4.3% | 990 |
| 2022 | $37,072,888▼14.4% | $41,968,785▲7.8% | $61,681,006▼16.3% | $126,586,860▲55.2% | 990 |
| 2021 | $43,313,392▲8.7% | $38,933,529▼3.9% | $73,696,982▲9.7% | $81,550,518▲1.7% | 990 |
| 2020 | $39,847,320▲10.0% | $40,513,307▼1.2% | $67,161,593▲5.8% | $80,193,323▲9.4% | 990 |
| 2019 | $36,230,866▲15.9% | $41,016,030▲23.8% | $63,505,387▲0.7% | $73,280,105▼1.2% | 990 |
| 2018 | $31,249,334▲0.1% | $33,125,028▲4.0% | $63,067,652▼12.1% | $74,178,732▼13.0% | 990 |
| 2017 | $31,226,281▼64.2% | $31,854,012▼2.3% | $71,749,749▲1.2% | $85,281,060▲1.7% | 990 |
| 2016 | $87,151,283▲176% | $32,600,250▼1.9% | $70,872,485▲388% | $83,864,265▲115% | 990 |
| 2015 | $31,520,035▼0.5% | $33,241,519▼0.5% | $14,509,621▼10.5% | $38,939,866▼8.5% | 990 |
| 2014 | $31,664,045▼30.9% | $33,423,718▼19.8% | $16,216,019▼10.1% | $42,554,882▼10.7% | 990 |
| 2013 | $45,826,260 | $41,674,522▼5.7% | $18,038,454▲48.2% | $47,653,059▲9.5% | 990 |
| 2012 | — | $44,210,577▼7.1% | $12,175,674▼5.1% | $43,517,471▼4.3% | 990 |
| 2011 | — | $47,590,897▼6.2% | $12,834,894▼41.3% | $45,477,682▼19.1% | 990 |
| 2010 | — | $50,720,552▲52.2% | $21,873,068▲18.3% | $56,185,035▲59.7% | 990 |
| 2008 | — | $33,326,967 | $18,486,711 | $35,189,559 | 990 |
Original Form 990 PDFs (the Form column) are served by ProPublica Nonprofit Explorer, as filed with the IRS. Create a free account to download the CSV report.
Leadership & compensation (FY2024)
Highest-paid: James R Heath Phd — $509,772 (1.07% of total expenses)
| Name | Title | Hours/week | Compensation |
|---|---|---|---|
| James R Heath Phd | President/professor | 55 | $509,772 |
| Nitin Baliga Phd | Svp Dir of Integrative Science/prof | 55 | $343,731 |
| Kathy Scanlan | Coo/treasurer | 55 | $323,595 |
| Andrew Magis | Director of Data Science | 50 | $282,804 |
| Robert L Mortiz Phd | Professor | 50 | $271,421 |
| Sui Huang Md Phd | Professor | 50 | $237,123 |
| Leroy Hood Md Phd | Director | 50 | $187,500 |
| Erika Kreger | Director of Development | 50 | $186,033 |
| Naeha Subramanian Phd | Associate Professor | 50 | $181,654 |
| Amy Compton-phillips Md | Director | 0.5 | — |
| Ari Robicsek Md | Director | 0.5 | — |
| Brian V Turner | Director | 0.5 | — |
| Charles Watts Md | Board Chair | 1 | — |
| Craig Mundie | Director | 0.5 | — |
| Daniel T Ling | Director | 0.5 | — |
| David Sabey | Director | 0.5 | — |
| Douglas Howe | Director | 0.5 | — |
| Heather Redman | Director | 0.5 | — |
| Hoda Asmar Md | Director (part Year) | 0.5 | — |
| Jim Martin | Director - Thru 6/24 | 0.5 | — |
Top vendors & contractors (FY2024)
| Contractor | Services | Paid |
|---|---|---|
| University of Washington | Research Grant Subcontractor | $1,751,408 |
| Swedish Health Services | Research Grant Subcontractor | $1,332,547 |
| Biocentriq Inc | Research Grant Subcontractor | $1,031,017 |
| Seattle Childrens Research Institute | Research Grant Subcontractor | $799,483 |
| Regents of the University of California | Research Grant Subcontractor | $720,890 |
Grants received · $13.4M total
70 grants to Institute For Systems Biology totaling $13.4M, reported by foundations on their Schedule I filings — showing the 15 most recent.
| Grantmaker | Purpose | Year | Amount |
|---|---|---|---|
| Mayo Clinic Group Return | Support charitable purpose | 2024 | $74,577 |
| Mayo Clinic | Support charitable purpose | 2024 | $19,130 |
| American Online Giving Foundation Inc | General support | 2024 | $7,421 |
| Mayo Clinic Group Return | Support research program | 2023 | $445,307 |
| President and Fellows of Harvard College | Sponsored research sub-award | 2023 | $141,250 |
| Fred Hutchinson Cancer Center | Research support/subawards | 2023 | $110,341 |
| Northwestern University | Support of research activities | 2023 | $69,366 |
| Cornell University | Research | 2023 | $43,931 |
| Mayo Clinic | Support charitable purpose | 2023 | $21,100 |
| Fidelity Investments Charitable Gift Fund | For grant recipient's exempt purposes | 2023 | $15,500 |
| Mayo Clinic Group Return | Support charitable purpose | 2022 | $1,007,351 |
| Providence Health & Services Washington | Operational support | 2022 | $741,940 |
| Parker Institute For Cancer Immunotherapy | Support research in field of cancer immunotherapy | 2022 | $547,924 |
| President and Fellows of Harvard College | Sponsored research sub-award | 2022 | $361,086 |
| Seattle Childrens Hospital | Pediatric medical research grant subaward | 2022 | $349,566 |
Grants made · $267K in FY2014
1 grant totaling $267K in FY2014. All grants made by Institute For Systems Biology →
| Recipient | Purpose | Amount |
|---|---|---|
| Center For Infectious Disease Research (cidr) | To support disease research | $266,653 |
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Frequently asked questions
- Is Institute For Systems Biology a legitimate nonprofit?
- Yes. Institute For Systems Biology is a 501(c)(3) organization registered with the U.S. Internal Revenue Service under EIN 91-2003593, based in Seattle, Washington. Donations are tax-deductible.
- What is Institute For Systems Biology's EIN?
- Institute For Systems Biology's Employer Identification Number (EIN) is 91-2003593.
- How much revenue does Institute For Systems Biology report?
- Institute For Systems Biology reported $42,255,091 in total revenue on its fiscal year 2024 IRS Form 990 filing.
- How much of Institute For Systems Biology's spending goes to programs?
- Institute For Systems Biology spends about 71% of its total expenses on programs, based on its latest IRS Form 990.
- What financial grade does Institute For Systems Biology have?
- CharityIndex grades Institute For Systems Biology B+, based on program efficiency and fundraising cost.
- How much does Institute For Systems Biology's highest-paid employee make?
- The highest reported compensation on Institute For Systems Biology's latest Form 990 is $509,772, paid to James R Heath Phd (President/professor).
More nonprofits in Seattle
Explore more
Data for Institute For Systems Biology (EIN 91-2003593) comes from the IRS Business Master File and e-filed Form 990 returns, via CharityIndex. Figures reflect what the organization reported to the IRS for each fiscal year.